足球波胆

科研进展

足球波胆JIEGOUYANJIUJIESHISNX11CANYUDIAOKONGNEITIRONGMEITIFENXUANYUNSHUDEJIZHI

  

  NEITI-RONGMEITISHINEITUNWUZHIJIANGJIEDEZHONGYAOTUJINGZHIYI,QIYICHANGKEDAOZHISHENJINGTUIXINGXINGLEIJIBINGDEFASHENG。SHUANGLINSUANHUADELINZHIXIANJICHUNPI(3,5)P2SHIWEIYUWANQINEITIHENEITIRONGMEITISHANGDEZHILEIXINHAOFENZI,SHIWEICHIXIBAONEITIWENDINGDEGUANJIANFENZI,CANYUDIAOKONGNEITI-RONGMEITIYUNSHU,DANMUQIANDUIQIXIAOYINGZIDANBAILEJIEJIAOSHAO,YOUQISHIZAIBURUDONGWUXITONGZHONG,ZHIJINWEIYOUPI(3,5)P2HEFENXUANYUNSHUXIANGGUANDANBAIJIEHEDEJIEGOUBEIBAODAO。 

足球波胆  ZHONGKEYUANGUANGZHOUSHENGWUYIYAOYUJIANKANGYANJIUYUANLIUJINGSONGTUANDUIHESHUXIAODONGTUANDUIHEZUO,ZAIQIANQIDEYANJIUZHONGFAXIANYIGEFENXUANDANBAISNX11KEYITEYIXINGSHIBIEPI(3,5)P2HEPI3P,BINGCANYUDIAOKONGNEITIWENTAI(JBC, 2013)。SNX11SUOSHUDESorting NexinJIAZUDANBAITONGGUOGONGYOUDEPXJIEGOUYUSHIBIEBUTONGZHONGLEIDEPIXIAOFENZI,ZAIBAONEIWUZHIYUNSHUFENXUANZHONGQIZHEZHONGYAOZUOYONG。SUIRANMUQIANYIYOUSANGEHANPXJIEGOUYUDANBAIHEPI3PDEFUHEWUJIEGOUDEDAOJIEXI,DANJINERSHINIANDEYANJIUZHONGDOUWEIYOUBAODAOPXHEDUOLINSUANHUADEPIXIAOFENZIDEFUHEWUJIEGOU,QIDUOLINSUANHUALINZHISHIBIEJIZHIYIZHICUNZAIDUOZHONGJIEDU。 

  ZAIQIANQIGONGZUOJICHUSHANG,LIUJINGSONGTUANDUIJINQIJIEXILESNX11HEPI(3,5)P2JIEHEDEFUHEWUJIEGOUYIJIYIZHONGMONIPI3PJIEHEZHUANGTAIDEJIEGOU,JIESHILEPXJIEGOUYUSHIBIEBUTONGZHONGLEILINZHIDEJIZHI。JIEGOUXIANSHI,SNX11LINZHIJIEHEKOUDAIDEPPII-loopDECDUANKEYIXINGCHENG“DAKAI”HE“GUANBI”LIANGZHONGGOUXIANG,LAIFENBIESHIBIEPI(3,5)P2HEPI3P。ERJINYIBUDEGONGNENGYANJIUFAXIANV-ATPaseKENENGSHISNX11DEHUOWUDANBAIZHIYI,SNX11KENENGSHIHETADETONGYUANDANBAISNX10JINGZHENGXINGJIEHEV-ATPase,TONGGUOYINGXIANGQIYUNSHUFANGXIANGLAIDIAOKONGNEITIXINGTAI。CIWAI,GAIYANJIUHAIJIEHEFENZIDONGLIXUEJISUANFAXIANSNX11DEα5LUOXUANKEYIZAIMOJIEHESHICANYUHUOWUDANBAIYUNSHUDEDIAOJIE。GAIJIEGOUYANJIUKEYIBANGZHUYUCEHANPXJIEGOUYUDEDANBAIDELINZHIJIEHETEYIXING,LEJIEQIJIEHEBUTONGPIERCHANSHENGDEXIAYOUSHENGLIGONGNENG。JIYUJINLAIBEIBAODAODESNX11ZAIMODANBAIRONGMEITIJIANGJIEYIJIZAIBINGDUGANRANGUOCHENGZHONGQIDEDIAOKONGZUOYONG,JIEXISNX11SHIBIELINZHIDEJIEGOUTEZHENGWEISHENRUTANSUONEITIRONGMEITIYUNSHUDIAOKONGDEJIZHITIGONGLEZHONGYAOXIANSUO。 

  GAICHENGGUOYOULIUJINGSONGYANJIUZUHESHUXIAODONGYANJIUZULIANHEFABIAOZAIJournal of Molecular BiologySHANG,XUTINGTINGFUYANJIUYUANSHILUNWENDIYIZUOZHE,LIUJINGSONGYANJIUYUANWEITONGXUNZUOZHE。KETIDEDAOGUOJIAZHONGDIANYANFAJIHUA、GUOJIAZIRANKEXUEJIJIN、GUANGDONGSHENGSHENGWUYIYAOJISUANZHONGDIANSHIYANSHI、GUANGDONGSHENGZIRANKEXUEJIJINDENGXIANGMUDEJINGFEIZHICHI。 

  

  

  

  ZUOTUWEISNX11HEPI(3,5)P2DEFUHEWUJIEGOU,YOUTUWEIBUTONGZHUANGTAIDESNX11DEJIEGOUBIDUITU。 

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